188 research outputs found

    Thermal Radiation from Nucleons and Mesons

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    Thermal photon emission rates due to meson-nucleon interactions have been evaluated. An exhaustive set of reactions involving p(\bar p), n(\bar n), rho, omega, a_1, pi and eta is seen to provide a sizeable contribution to the emission rate from hot hadronic matter. Contributions from baryonic resonances are found to be negligibly small

    A carbon monoxide ‘single breath’ method to measure total haemoglobin mass: a feasibility study

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    NEW FINDINGS: What is the central question of this study? Is it possible to modify the CO-rebreathing method to acquire reliable measurements of haemoglobin mass in ventilated patients? What is the main finding and its importance? A 'single breath' of carbon monoxide with a subsequent 30 sec breath hold provides almost as exact a measure of haemoglobin mass as the established optimized CO-rebreathing method when applied to healthy subjects. The modified method has now to be checked in ventilated patients before it can be used to quantify the contributions of blood loss and of dilution to the severity of anaemia. ABSTRACT: Anaemia is defined by the concentration of haemoglobin ([Hb]). However, this value is dependent upon both the total circulating haemoglobin mass (tHb-mass) and the plasma volume (PV) - neither of which are routinely measured. Carbon monoxide- (CO) rebreathing methods have been successfully used to determine both PV and tHb-mass in various populations. However, these methods are not yet suitable for ventilated patients. This study aimed to modify the CO-rebreathing procedure such that a single inhalation of a CO bolus would enable its use in ventilated patients. Eleven healthy volunteers performed four CO-rebreathing tests in a randomized order, inhaling an identical CO-volume. In two tests, CO was rebreathed for 2min (oCOR), and in the other two tests, a single inhalation of a CO bolus was conducted with a subsequent breath hold of 15sec (Procnew 15sec) or 30sec (Procnew 30sec). Subsequently, the CO volume in the exhaled air was continuously determined for 20 min. The amount of CO exhaled after 7min (after 20min) for oCOR was 3.1 ±0.3ml (5.9 ±1.1ml); for Procnew 15sec, 8.7 ±3.6ml (12.0 ±4.4ml); and for Procnew 30sec, 5.1 ±2.0ml (8.4 ±2.6ml)). tHb-mass determined by oCOR was 843 ±293g, from Procnew 15sec 821 ±288g (difference: p <0.05), and from Procnew 30sec 849 ±311g. Bland-Altman plots demonstrated slightly lower tHb-mass values for Procnew 15sec compared with oCOR (-21.8 ±15.3g) and similar values for Procnew 30sec. In healthy volunteers, a single inhalation of a CO bolus, preferably followed by a 30 sec breath hold, can be used to determine tHb-mass. These results must now be validated for ventilated patients. This article is protected by copyright. All rights reserved

    L-Tryptophan Production by Auxotrophic and Analogue Resistant Mutants of Aureobacterium flavescens

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    A number of tyrosine plus phenylalanine double auxotrophic mutants were isolated by N-methyl-N-nitro-N-nitrosoguanidine (MNNG) treatment of a locally isolated strain of Aureobacterium flavescens of which 11A39 and 11A17 were selected on the basis of their tryptophan production in a mineral salt medium over other isolated mutant strains. The mutational block in the aromatic amino acid biosynthetic pathway of the selected double auxotrophs were determined. By controlling pH of the production medium to near neutrality, the active growth period could be extended up to 72 h and more tryptophan was accumulated compared to pH unregulated culture where the active growth ceased after 48 h. Further improvement of the tryptophan production has been achieved by stepwise isolation of a mutant strain resistant to the tryptophan analogues p-fluorotryptophan (FT) and 5-methyl tryptophan (MT) from the 11A39. Demand for L-tryptophan as food additive and therapeutic agent is increasing day by day throughout the World, particularly in the underdeveloped and developing countries like India. Still to date India depends on other countries for L-tryptophan. The aim of this work is to develop a potent high yielding, feed back insensitive mutant strain and optimization of its medium pH for maximum production of tryptophan

    Nuclear response functions for the N-N*(1440) transition

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    Parity-conserving and -violating response functions are computed for the inclusive electroexcitation of the N*(1440)(Roper) resonance in nuclear matter modeled as a relativistic Fermi gas. Using various empirical parameterizations and theoretical models of the N-N*(1440) transition form factors, the sensitivity of the response functions to details of the structure of the Roper resonance is investigated. The possibility of disentangling this resonance from the contribution of Delta electroproduction in nuclei is addressed. Finally, the contributions of the Roper resonance to the longitudinal scaling function and to the Coulomb sum rule are also explored.Comment: 25 pages, 10 figures. Minor changes in the Introduction. Accepted in NP

    Dynamical coupled-channel approaches on a momentum lattice

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    Dynamical coupled-channel approaches are a widely used tool in hadronic physics that allow to analyze different reactions and partial waves in a consistent way. In such approaches the basic interactions are derived within an effective Lagrangian framework and the resulting pseudo-potentials are then unitarized in a coupled-channel scattering equation. We propose a scheme that allows for a solution of the arising integral equation in discretized momentum space for periodic as well as twisted boundary conditions. This permits to study finite size effects as they appear in lattice QCD simulations. The new formalism, at this stage with a restriction to S-waves, is applied to coupled-channel models for the sigma(600), f0(980), and a0(980) mesons, and also for the Lambda(1405) baryon. Lattice spectra are predicted.Comment: 7 pages, 4 figure

    A unified meson-baryon potential

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    We study the spectra of mesons and baryons, composed of light quarks, in the framework of a semirelativistic potential model including instanton induced forces. We show how a simple modification of the instanton interaction in the baryon sector allows a good description of the meson and the baryon spectra using an interaction characterized by a unique set of parameters.Comment: 7 figure

    Mechanism of Pion Production in alphaalphap Scattering at 1 GeV/nucleon

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    The one-pion and two-pion production in the p(alpha, alpha prime)X reaction at an energy of E{alpha} = 4.2 GeV has been studied by simultaneous registration of the scattered alpha particles and the secondary pion or proton. The obtained results demonstrate that the inelastic alpha-particle scattering on the proton at the energy of the experiment proceeds either through excitation and decay of Delta resonance in the projectile or through excitation in the target proton of the Roper resonance, which decays mainly on a nucleon and a pion or a nucleon and a sigma meson - system of two pions in the isospin I = 0, S-wave.Comment: 16 pages, 10 figures. Submitted to Proceedings of the XX International Baldin Seminar on High - Energy Physics Problems, Dubna, October 4 - 9, 201

    What is the structure of the Roper resonance?

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    We investigate the structure of the nucleon resonance N^*(1440) (Roper) within a coupled-channel meson exchange model for pion-nucleon scattering. The coupling to pipiN states is realized effectively by the coupling to the sigmaN, piDelta and rhoN channels. The interaction within and between these channels is derived from an effective Lagrangian based on a chirally symmetric Lagrangian, which is supplemented by well known terms for the coupling of the Delta isobar, the omega meson and the 'sigma', which is the name given here to the strong correlation of two pions in the scalar-isoscalar channel. In this model the Roper resonance can be described by meson-baryon dynamics alone; no genuine N^*(1440) (3 quark) resonance is needed in order to fit piN phase shifts and inelasticities.Comment: 55 pages, 14 figure
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